HitPredict

Interactor 1: G5EGG2 (G5EGG2)
Homolog of S. Pombe Rad (Rad17-like protein)
Gene: hpr-17

Interactor 2: RFC4 (P53016)
Replication factor C subunit 4 (Activator 1 subunit 4)
Gene: rfc-4

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	12679813, 11778048, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003689 - DNA clamp loader activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006281 - DNA repair
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 514 Ce			1 334
+	Hs
		721934 RFC1_HUMAN (2-512): 3.86e-87: 292: 13.29		RFC4_HUMAN (8-333): 2.08e-90: 276: 41.03
+	Hs
		722179 RFC1_HUMAN (2-512): 3.86e-87: 292: 13.29		RFC5_HUMAN (1-332): 2.63e-81: 252: 33.53
+	Hs
		278999 RAD17_HUMAN (4-508): 1.12e-80: 266: 21.96		RFC4_HUMAN (8-333): 2.08e-90: 276: 41.03
+	Hs
		722068 RFC1_HUMAN (2-512): 3.86e-87: 292: 13.29		RFC2_HUMAN (13-332): 1.7e-79: 248: 29.38
+	Hs
		279002 RAD17_HUMAN (4-508): 1.12e-80: 266: 21.96		RFC5_HUMAN (1-332): 2.63e-81: 252: 33.53
+	Hs
		279000 RAD17_HUMAN (4-508): 1.12e-80: 266: 21.96		RFC2_HUMAN (13-332): 1.7e-79: 248: 29.38
+	Ce
		858450 Q18841_CAEEL (5-512): 2.52e-76: 258: 13.84		RFC4_CAEEL (1-334): 5.78e-82: 253: 100.00
+	Hs
		722180 RFC1_HUMAN (2-512): 3.86e-87: 292: 13.29		RFC3_HUMAN (14-334): 2.95e-62: 203: 21.90
+	Dm
		725318 RFC1_DROME (9-496): 5.25e-74: 254: 12.90		RFC2_DROME (2-334): 3.83e-77: 241: 27.93
+	Dm
		725339 RFC1_DROME (9-496): 5.25e-74: 254: 12.90		Q9VX15_DROME (4-334): 4.6e-77: 241: 37.80
+	Sc
		751312 RFC1_YEAST (3-470): 1.09e-73: 251: 13.39		RFC2_YEAST (15-331): 4.86e-78: 244: 36.28
+	Sc
		751260 RFC1_YEAST (3-470): 1.09e-73: 251: 13.39		RFC3_YEAST (5-334): 2.21e-77: 242: 34.52
+	Dm
		725336 RFC1_DROME (9-496): 5.25e-74: 254: 12.90		Q9VKW3_DROME (5-329): 7.57e-76: 238: 31.71
+	Ce
		218176 O44175_CAEEL (2-334): 8.1e-71: 230: 11.14		RFC5_CAEEL (12-334): 5.93e-76: 239: 31.36
+	Hs
		279003 RAD17_HUMAN (4-508): 1.12e-80: 266: 21.96		RFC3_HUMAN (14-334): 2.95e-62: 203: 21.90
+	Sc
		751310 RFC1_YEAST (3-470): 1.09e-73: 251: 13.39		RFC4_YEAST (15-331): 1.91e-68: 218: 30.92
+	Cj
		1006963 Q0P999_CAMJE (7-422): 5.95e-69: 231: 13.69		Q0P999_CAMJE (20-303): 3.85e-70: 228: 23.76
+	Sc
		747101 RFC1_YEAST (3-470): 1.09e-73: 251: 13.39		RFC5_YEAST (14-334): 3.39e-63: 206: 22.60
+	Dm
		725331 RFC1_DROME (9-496): 5.25e-74: 254: 12.90		Q9U9Q1_DROME (14-334): 1.41e-58: 194: 21.90
+	Ce
		1090164 Q18841_CAEEL (5-512): 2.52e-76: 258: 13.84		Q18547_CAEEL (14-333): 3.2e-53: 180: 20.63