Interactor 1: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Interactor 2: M3K3 (Q99759)
Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)
Gene: MAP3K3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 14743216
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~Pkinase, CDC37_N~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 378
Hs

1 626
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Last updated: 15 Jul 2024