Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2

Interactor 2: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 20067962
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001530 - lipopolysaccharide binding
GO:0006954 - inflammatory response
GO:0009986 - cell surface
GO:0032733 - positive regulation of interleukin-10 production
GO:0032735 - positive regulation of interleukin-12 production
and 5 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 784
Hs

1 215
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Dm

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Last updated: 15 Jul 2024