Interactor 1: RPM1 (Q17551)
E3 ubiquitin-protein ligase rpm-1 (EC 2.3.2.33) (Pam/highwire/rpm-1 protein) (Regulator of presynaptic morphology protein 1) (Synapse defective protein 3)
Gene: rpm-1

Interactor 2: FBSP1 (Q18223)
F-box/SPRY domain-containing protein 1 (F-box synaptic protein 1)
Gene: fsn-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 29997255, 25326385, 27979965, 15208641
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008582 - regulation of synaptic assembly at neuromuscular junction
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
GO:0030517 - negative regulation of axon extension
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 3766
Ce

1 332
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+ Dm
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Last updated: 15 Jul 2024