HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: FRPD4 (Q14CM0)
FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso)
Gene: FRMPD4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.80	0.687

Property	Details
Experiments	24550280, 30126976
Identification Methods	phage display, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 1322
+	Hs
		1135552 DLG3_HUMAN (137-904): 0: 569: 66.11		FRPD4_HUMAN (1-1322): 0: 2166: 100.00
+	Mm
		59272 DLG4_MOUSE (175-904): 0: 551: 71.31		FRPD4_MOUSE (1-1322): 0: 2167: 90.70
+	Hs
		1006066 DLG4_HUMAN (175-904): 0: 550: 71.31		FRPD4_HUMAN (1-1322): 0: 2166: 100.00
+	Hs
		1125290 DLG3_HUMAN (137-904): 0: 569: 66.11		FAK2_HUMAN (191-539): 1.74e-66: 246: 20.87
+	Mm
		757457 DLG4_MOUSE (175-904): 0: 551: 71.31		FAK1_MOUSE (202-540): 1.15e-68: 253: 23.18
+	Hs
		1006062 DLG4_HUMAN (175-904): 0: 550: 71.31		FAK2_HUMAN (191-539): 1.74e-66: 246: 20.87
+	Mm
		3698 DLG4_MOUSE (175-904): 0: 551: 71.31		A0A140LIW3_MOUSE (776-940): 1.26e-63: 241: 47.65
+	Mm
		1223740 DLG4_MOUSE (175-904): 0: 551: 71.31		MAGI3_MOUSE (14-161): 3.19e-39: 161: 23.94
+	Mm
		1223628 DLG4_MOUSE (175-904): 0: 551: 71.31		Q8BXG0_MOUSE (193-312): 2.26e-41: 150: 56.67
+	Hs
		1325307 PALS1_HUMAN (1-472): 2.58e-18: 92.2: 13.13		MAGI1_HUMAN (14-158): 1.22e-25: 117: 17.50