HitPredict

Interactor 1: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SAM_1
Common GO terms	GO:0007165 - signal transduction GO:0032991 - protein-containing complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 1620
+	Hs
		773304 MYH10_HUMAN (44-609): 2.55e-18: 93.5: 15.52		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		773080 MYH9_HUMAN (300-869): 4.94e-13: 76.4: 11.41		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		1292207 LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		1336249 LIPB2_HUMAN (175-407): 4.04e-09: 63.2: 12.88		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		711883 LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00		LTK_HUMAN (606-1458): 2.7e-178: 559: 53.24
+	Hs
		1095537 LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00		NTRK2_HUMAN (1093-1375): 7.39e-64: 236: 41.44
+	Hs
		411847 LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		541461 LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		710604 MYH9_HUMAN (300-869): 4.94e-13: 76.4: 11.41		EPHA3_HUMAN (943-1427): 1.05e-119: 403: 25.05
+	Hs
		411475 MYH10_HUMAN (44-609): 2.55e-18: 93.5: 15.52		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		1159510 LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51		NTRK2_HUMAN (1093-1375): 7.39e-64: 236: 41.44
+	Hs
		411474 MYH9_HUMAN (300-869): 4.94e-13: 76.4: 11.41		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412199 LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412274 LIPB2_HUMAN (175-407): 4.04e-09: 63.2: 12.88		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		541571 LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07