HitPredict

Interactor 1: GLC7A (Q27497)
Serine/threonine-protein phosphatase PP1-alpha (EC 3.1.3.16) (CeGLC-7-alpha) (Glc seven-like phosphatase 1)
Gene: gsp-1

Interactor 2: Q9N537 (Q9N537)
Protein phosphatase inhibitor 2
Gene: szy-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	19123269, 28103229
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 329 Ce			1 193
+	Ce
		821925 GLC7B_CAEEL (3-328): 0: 567: 82.93		Q9N537_CAEEL (1-193): 2.24e-64: 198: 100.00
+	Hs
		906500 PP1B_HUMAN (4-329): 0: 572: 89.88		IPP2B_HUMAN (1-177): 9.65e-50: 161: 32.60
+	Hs
		782715 PP1B_HUMAN (4-329): 0: 572: 89.88		IPP2_HUMAN (1-177): 1.14e-48: 159: 33.70
+	Hs
		905971 PP1A_HUMAN (1-326): 0: 570: 84.45		IPP2B_HUMAN (1-177): 9.65e-50: 161: 32.60
+	Hs
		782714 PP1A_HUMAN (1-326): 0: 570: 84.45		IPP2_HUMAN (1-177): 1.14e-48: 159: 33.70
+	Mm
		906370 PP1A_MOUSE (1-326): 0: 570: 84.15		IPP2_MOUSE (1-177): 1.55e-48: 158: 32.97
+	Hs
		737869 PP1G_HUMAN (1-329): 0: 564: 83.28		IPP2B_HUMAN (1-177): 9.65e-50: 161: 32.60
+	Hs
		737628 PP1G_HUMAN (1-329): 0: 564: 83.28		IPP2_HUMAN (1-177): 1.14e-48: 159: 33.70
+	Hs
		164069 PP1B_HUMAN (4-329): 0: 572: 89.88		IPP2C_HUMAN (1-181): 8.27e-45: 148: 23.40
+	Hs
		164068 PP1A_HUMAN (1-326): 0: 570: 84.45		IPP2C_HUMAN (1-181): 8.27e-45: 148: 23.40
+	Hs
		164067 PP1G_HUMAN (1-329): 0: 564: 83.28		IPP2C_HUMAN (1-181): 8.27e-45: 148: 23.40
+	Dm
		65576 PP1B_DROME (4-329): 0: 559: 85.63		A8JNP7_DROME (27-174): 2.15e-40: 140: 37.33
+	Dm
		65575 PP11_DROME (7-326): 0: 551: 82.50		A8JNP7_DROME (27-174): 2.15e-40: 140: 37.33
+	Dm
		65574 PP12_DROME (7-304): 0: 544: 87.25		A8JNP7_DROME (27-174): 2.15e-40: 140: 37.33
+	Dm
		819290 PP1B_DROME (4-329): 0: 559: 85.63		Q9V3C7_DROME (27-174): 6.14e-35: 123: 37.33
+	Dm
		65577 PP13_DROME (7-304): 0: 540: 86.58		A8JNP7_DROME (27-174): 2.15e-40: 140: 37.33
+	Dm
		819222 PP11_DROME (7-326): 0: 551: 82.50		Q9V3C7_DROME (27-174): 6.14e-35: 123: 37.33
+	Dm
		524639 PP12_DROME (7-304): 0: 544: 87.25		Q9V3C7_DROME (27-174): 6.14e-35: 123: 37.33
+	Dm
		984191 PP13_DROME (7-304): 0: 540: 86.58		Q9V3C7_DROME (27-174): 6.14e-35: 123: 37.33