HitPredict

Interactor 1: K1C24 (Q2M2I5)
Keratin, type I cytoskeletal 24 (Cytokeratin-24) (CK-24) (Keratin-24) (K24) (Type I keratin-24)
Gene: KRT24

Interactor 2: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 520
+	Hs
		729101 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K22E_HUMAN (83-427): 1.05e-121: 372: 55.65
+	Hs
		409094 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		380624 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Hs
		409134 K1C28_HUMAN (27-525): 1.47e-154: 451: 52.29		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		1055205 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		KRT81_HUMAN (1-502): 8.51e-104: 322: 39.69
+	Hs
		380645 K1C28_HUMAN (27-525): 1.47e-154: 451: 52.29		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Hs
		318814 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C75_HUMAN (2-516): 7.92e-95: 300: 48.22
+	Hs
		213963 K1C28_HUMAN (27-525): 1.47e-154: 451: 52.29		KRT86_HUMAN (1-499): 1.62e-103: 321: 39.88
+	Hs
		1101626 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C79_HUMAN (9-442): 1.75e-88: 283: 53.14
+	Hs
		1101623 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C71_HUMAN (4-502): 3.35e-87: 279: 48.74
+	Hs
		1062053 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C72_HUMAN (1-502): 4.44e-85: 274: 47.85
+	Hs
		380483 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C6B_HUMAN (76-448): 4.72e-80: 262: 59.25
+	Hs
		821665 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C6C_HUMAN (76-448): 1.24e-79: 261: 59.52
+	Hs
		531580 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C5_HUMAN (76-427): 3.19e-78: 258: 62.50
+	Hs
		1101629 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C74_HUMAN (1-502): 1.03e-76: 252: 47.06
+	Hs
		580134 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C4_HUMAN (6-443): 3.19e-73: 243: 55.10
+	Hs
		380494 K1C28_HUMAN (27-525): 1.47e-154: 451: 52.29		K2C6B_HUMAN (76-448): 4.72e-80: 262: 59.25
+	Hs
		517755 K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00		K2C3_HUMAN (83-428): 5.14e-68: 232: 62.07
+	Hs
		359509 K1C28_HUMAN (27-525): 1.47e-154: 451: 52.29		K2C6A_HUMAN (76-448): 1.02e-78: 258: 59.79
+	Hs
		517764 K1C28_HUMAN (27-525): 1.47e-154: 451: 52.29		K2C3_HUMAN (83-428): 5.14e-68: 232: 62.07