HitPredict

Interactor 1: PTK7 (Q13308)
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)
Gene: PTK7

Interactor 2: PPM1K (Q8N3J5)
Protein phosphatase Mn(2+)-dependent 1K (EC 3.1.3.16) (Branched-chain alpha-ketoacid dehydrogenase phosphatase) (BCKDH) (BDP) (EC 3.1.3.52) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C family member) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) ([3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase, mitochondrial)
Gene: PPM1K

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1070 Hs			1 372
+	Hs
		776952 PTK7_HUMAN (2-329): 4.58e-53: 204: 19.94		PPM1A_HUMAN (72-362): 4.25e-103: 310: 27.94
+	Hs
		777031 ALK_HUMAN (695-1067): 1.22e-52: 204: 32.90		PPM1A_HUMAN (72-362): 4.25e-103: 310: 27.94
+	Hs
		290924 PTK7_HUMAN (2-329): 4.58e-53: 204: 19.94		PPM1B_HUMAN (72-362): 1.82e-98: 302: 27.19
+	Hs
		641132 FGFR2_HUMAN (196-502): 4.79e-48: 187: 16.76		PPM1A_HUMAN (72-362): 4.25e-103: 310: 27.94
+	Hs
		290845 FGFR1_HUMAN (2-231): 1.1e-34: 145: 12.77		PPM1B_HUMAN (72-362): 1.82e-98: 302: 27.19
+	Hs
		1101774 PTK7_HUMAN (2-329): 4.58e-53: 204: 19.94		ILKAP_HUMAN (114-347): 8.99e-27: 111: 32.06
+	Hs
		179635 MUSK_HUMAN (130-422): 5.56e-12: 72: 21.93		ILKAP_HUMAN (114-347): 8.99e-27: 111: 32.06