Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM
Interactor 2: RHEB (Q15382)
GTP-binding protein Rheb (EC 3.6.5.-) (Ras homolog enriched in brain)
Gene: RHEB
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15854902 |
| Identification Methods | pull down, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PI3_PI4_kinase~Ras |
| Common GO terms | GO:0005829 - cytosol GO:0007165 - signal transduction GO:0051726 - regulation of cell cycle |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025