HitPredict

Interactor 1: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS

Interactor 2: PCDGD (Q9Y5G3)
Protocadherin gamma-B1 (PCDH-gamma-B1)
Gene: PCDHGB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030426 - growth cone
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1948 Hs			1 927
+	Hs
		1102778 PTPRS_HUMAN (1-1948): 0: 1707: 100.00		PCDG6_HUMAN (1-912): 0: 998: 52.01
+	Hs
		1102777 PTPRS_HUMAN (1-1948): 0: 1707: 100.00		PCDG7_HUMAN (1-912): 0: 988: 51.47
+	Hs
		522762 PTPRF_HUMAN (1-1948): 0: 1534: 65.68		PCDGD_HUMAN (1-912): 0: 1059: 100.00
+	Hs
		522763 PTPRF_HUMAN (1-1948): 0: 1534: 65.68		PCDG5_HUMAN (1-912): 0: 1004: 51.57
+	Hs
		1102775 PTPRS_HUMAN (1-1948): 0: 1707: 100.00		PCDGE_HUMAN (1-440): 1.02e-100: 337: 23.86
+	Hs
		659067 PTPRG_HUMAN (843-1945): 0: 789: 26.42		PCDGK_HUMAN (31-912): 0: 960: 47.76
+	Hs
		522743 PTPRF_HUMAN (1-1948): 0: 1534: 65.68		PCDBG_HUMAN (456-922): 2.98e-43: 171: 15.85
+	Hs
		1201830 SDK2_HUMAN (19-1281): 2.32e-120: 426: 15.93		PCDGD_HUMAN (1-912): 0: 1059: 100.00
+	Hs
		658948 PTPRD_HUMAN (4-1068): 1.21e-104: 375: 19.18		PCDG6_HUMAN (1-912): 0: 998: 52.01
+	Hs
		1144690 PTPRK_HUMAN (266-1016): 3.38e-41: 169: 13.69		PCDGD_HUMAN (1-912): 0: 1059: 100.00
+	Hs
		1366857 PTPRU_HUMAN (211-781): 1.34e-19: 98.5: 13.55		PCDGD_HUMAN (1-912): 0: 1059: 100.00
+	Hs
		1366856 PTPRU_HUMAN (211-781): 1.34e-19: 98.5: 13.55		PCDGM_HUMAN (15-912): 0: 958: 47.52
+	Hs
		658945 PTPRD_HUMAN (4-1068): 1.21e-104: 375: 19.18		PCDGG_HUMAN (1-440): 5.97e-98: 329: 24.18
+	Hs
		1366855 PTPRU_HUMAN (211-781): 1.34e-19: 98.5: 13.55		PCDB3_HUMAN (1-764): 0: 591: 44.72
+	Hs
		1366854 PTPRU_HUMAN (211-781): 1.34e-19: 98.5: 13.55		PCDB7_HUMAN (1-772): 0: 588: 44.98
+	Hs
		658936 PTPRD_HUMAN (4-1068): 1.21e-104: 375: 19.18		PCDBG_HUMAN (456-922): 2.98e-43: 171: 15.85
+	Hs
		658946 PTPRD_HUMAN (4-1068): 1.21e-104: 375: 19.18		PCDB6_HUMAN (504-922): 1.64e-41: 165: 15.23
+	Hs
		1144687 PTPRK_HUMAN (266-1016): 3.38e-41: 169: 13.69		PCDGG_HUMAN (1-440): 5.97e-98: 329: 24.18
+	Hs
		1366848 PTPRU_HUMAN (211-781): 1.34e-19: 98.5: 13.55		PCDGG_HUMAN (1-440): 5.97e-98: 329: 24.18