Interactor 1: TOP3A (Q13472)
DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha)
Gene: TOP3A
Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 1.00 | 0.857 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Helicase_C~Topoisom_bac, DEAD~Toprim |
| Common GO terms | GO:0005654 - nucleoplasm |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
