Protein: DHCR7
7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Delta7-sterol reductase) (Sterol Delta(7)-reductase) (Sterol reductase SR-2)

Gene: DHCR7
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q9UBM7

Gene Ontology (top 5):
GO:0005640 - nuclear outer membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006695 - cholesterol biosynthetic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

529845

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.601

High

123749

PGRC1
Membrane-associated progesterone receptor component 1

1

2

High-throughput

0.536

High

654867

CALX
Calnexin

1

2

High-throughput

0.536

High

1282496

NCLN
BOS complex subunit NCLN

1

1

High-throughput

0.536

High

1283318

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

1332034

SG196
Protein O-mannose kinase

1

1

High-throughput

0.536

High

206112

TGON2
Trans-Golgi network integral membrane protein 2

2

2

High-throughput

0.533

High

375031

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

High-throughput

0.533

High

916045

RHOB
Rho-related GTP-binding protein RhoB

2

17

High-throughput

0.533

High

408695

KPCB
Protein kinase C beta type

2

2

High-throughput

0.521

High

784109

KPCI
Protein kinase C iota type

2

2

High-throughput

0.521

High

1169991

RHG36
Rho GTPase-activating protein 36

2

1

High-throughput

0.521

High

1224239

DOCK3
Dedicator of cytokinesis protein 3

2

2

High-throughput

0.521

High

152051

TOR1A
Torsin-1A

1

1

High-throughput

0.515

High

234157

FADS1
Acyl-CoA

1

1

High-throughput

0.515

High

1345083

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.515

High

1233060

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

228955

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

274025

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

348980

RASN
GTPase NRas

1

7

High-throughput

0.479

High

350643

RASK
GTPase KRas

1

7

High-throughput

0.479

High

377772

GCR
Glucocorticoid receptor

1

3

Small-scale

0.479

High

390594

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

High-throughput

0.479

High

391233

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

436556

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.479

High

455963

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

476504

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.479

High

527859

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

545679

RAC2
Ras-related C3 botulinum toxin substrate 2

1

14

High-throughput

0.479

High

573961

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.479

High

595458

LMNB1
Lamin-B1

1

5

High-throughput

0.479

High

609589

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.479

High

738284

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

2

High-throughput

0.479

High

795325

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.479

High

825584

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

839205

EMD
Emerin

1

2

High-throughput

0.479

High

845788

RAB9A
Ras-related protein Rab-9A

1

5

High-throughput

0.479

High

847711

BAP31
B-cell receptor-associated protein 31

1

3

High-throughput

0.479

High

890487

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.479

High

892655

RAC3
Ras-related C3 botulinum toxin substrate 3

1

16

High-throughput

0.479

High

894549

CDC42
Cell division control protein 42 homolog

1

17

High-throughput

0.479

High

895305

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

901010

RHOA
Transforming protein RhoA

1

16

High-throughput

0.479

High

913158

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

925696

RAC1
Ras-related C3 botulinum toxin substrate 1

1

16

High-throughput

0.479

High

935330

H31
Histone H3.1

1

3

High-throughput

0.479

High

951430

RHOG
Rho-related GTP-binding protein RhoG

1

14

High-throughput

0.479

High

961872

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.479

High

990728

CKAP4
Cytoskeleton-associated protein 4

1

4

High-throughput

0.479

High

1017837

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1124465

TM41B
Transmembrane protein 41B

1

1

High-throughput

0.479

High

1166031

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1198700

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

5

High-throughput

0.479

High

1204855

GOLI
E3 ubiquitin-protein ligase RNF130

1

5

High-throughput

0.479

High

1240350

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1240819

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.479

High

1255716

RBCC1
RB1-inducible coiled-coil protein 1

1

1

High-throughput

0.479

High

1256072

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.479

High

1284135

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

1294098

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1300805

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1303616

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

1319286

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.479

High

1328880

DJC25
DnaJ homolog subfamily C member 25

1

3

High-throughput

0.479

High

1329313

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

3

High-throughput

0.479

High

1333608

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1344337

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.479

High

1348607

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

1350575

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1354115

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1304953

NECD
Necdin

1

1

High-throughput

0.470

High

169653

BET1
BET1 homolog

1

0

High-throughput

0.458

High

323249

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

329994

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

514735

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

738422

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.458

High

750512

COIL
Coilin

1

0

High-throughput

0.458

High

873165

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

0

High-throughput

0.458

High

881691

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

1033586

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.458

High

1042739

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1072981

DHC24
Delta(24)-sterol reductase

1

0

Small-scale

0.458

High

1168727

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1282669

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

1303012

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1241657

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.445

High

119550

LEG9
Galectin-9

1

1

High-throughput

0.437

High

120694

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.437

High

178027

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.437

High

178838

STX7
Syntaxin-7

1

3

High-throughput

0.437

High

179868

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.437

High

297686

RHBT1
Rho-related BTB domain-containing protein 1

1

15

High-throughput

0.437

High

320234

ERR2
Steroid hormone receptor ERR2

1

3

High-throughput

0.437

High

326805

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.437

High

553957

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

564719

RHOQ
Rho-related GTP-binding protein RhoQ

1

17

High-throughput

0.437

High

572694

VGFR1
Vascular endothelial growth factor receptor 1

1

2

High-throughput

0.437

High

591132

BTF3
Transcription factor BTF3

1

2

High-throughput

0.437

High

591706

RAB3B
Ras-related protein Rab-3B

1

2

High-throughput

0.437

High

592047

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.437

High

652497

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

670260

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.437

High

674553

UFO
Tyrosine-protein kinase receptor UFO

1

2

High-throughput

0.437

High

721676

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

824490

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

828043

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

2

High-throughput

0.437

High

830806

ARL4D
ADP-ribosylation factor-like protein 4D

1

5

High-throughput

0.437

High

831068

CTCF
Transcriptional repressor CTCF

1

1

Small-scale

0.437

High

844777

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.437

High

852663

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.437

High

901263

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.437

High

903578

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.437

High

909268

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

941541

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

952672

H33
Histone H3.3

1

3

High-throughput

0.437

High

999166

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.437

High

1036169

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.437

High

1061660

CUL7
Cullin-7

1

1

High-throughput

0.437

High

1070435

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.437

High

1076799

RHOH
Rho-related GTP-binding protein RhoH

1

16

High-throughput

0.437

High

1108966

PKHG6
Pleckstrin homology domain-containing family G member 6

1

2

High-throughput

0.437

High

1156740

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

1163892

RICTR
Rapamycin-insensitive companion of mTOR

1

2

High-throughput

0.437

High

1172101

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1183589

RHOU
Rho-related GTP-binding protein RhoU

1

19

High-throughput

0.437

High

1188982

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1198212

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1221004

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

1

High-throughput

0.437

High

1230414

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1237805

ARL10
ADP-ribosylation factor-like protein 10

1

6

High-throughput

0.437

High

1263925

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1269242

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.437

High

1269830

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

1292892

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

1296758

RHOV
Rho-related GTP-binding protein RhoV

1

16

High-throughput

0.437

High

1317632

RHBT2
Rho-related BTB domain-containing protein 2

1

15

High-throughput

0.437

High

1330969

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.437

High

1331526

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1335370

RHOF
Rho-related GTP-binding protein RhoF

1

19

High-throughput

0.437

High

1344215

SAR1A
Small COPII coat GTPase SAR1A

1

7

High-throughput

0.437

High

1346197

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1349376

PD1L1
Programmed cell death 1 ligand 1

1

2

High-throughput

0.437

High

1354112

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1354113

TNIK
TRAF2 and NCK-interacting protein kinase

1

1

High-throughput

0.437

High

1354116

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.437

High

384014

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.426

High

1354114

AGO2
Protein argonaute-2

1

0

High-throughput

0.426

High

1153

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.407

High

135296

E2F3
Transcription factor E2F3

1

1

Small-scale

0.407

High

398125

ISG15
Ubiquitin-like protein ISG15

1

1

Small-scale

0.407

High

497723

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.407

High

1057697

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.407

High

1153426

PKHA7
Pleckstrin homology domain-containing family A member 7

1

3

High-throughput

0.407

High

146417

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.279

Low

296992

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.279

Low

984836

RN5A
2-5A-dependent ribonuclease

1

0

High-throughput

0.279

Low

429946

CATL1
Procathepsin L

1

0

High-throughput

0.249

Low

622539

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.249

Low

837758

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

897143

ACTZ
Alpha-centractin

1

0

High-throughput

0.249

Low

914428

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

940590

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.249

Low

961307

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.249

Low

1049169

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

1080435

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1148840

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1152160

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1166881

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

1239757

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

1260941

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

1298679

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

1328835

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

0

High-throughput

0.249

Low

1342776

PPA6
Lysophosphatidic acid phosphatase type 6

1

0

High-throughput

0.249

Low

1343356

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.249

Low

1346511

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.249

Low

1354117

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024