HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 39098523
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0030154 - cell differentiation
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 457
+	Hs
		1108256 SQSTM_HUMAN (1-440): 0: 760: 100.00		LIMD1_HUMAN (70-457): 8.76e-55: 195: 16.51
+	Mm
		1225680 SQSTM_MOUSE (1-440): 0: 731: 90.72		LIMD1_MOUSE (123-457): 8.1e-55: 195: 18.18
+	Hs
		878452 SQSTM_HUMAN (1-440): 0: 760: 100.00		PAXI_HUMAN (196-397): 6.31e-29: 121: 21.76
+	Hs
		1108042 SQSTM_HUMAN (1-440): 0: 760: 100.00		PDLI5_HUMAN (1-269): 1.13e-22: 102: 24.82
+	Hs
		1107997 SQSTM_HUMAN (1-440): 0: 760: 100.00		LPP_HUMAN (71-391): 1.55e-20: 96.3: 17.77
+	Hs
		1107748 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRIP6_HUMAN (335-456): 5.98e-17: 84.7: 30.40
+	Hs
		1108044 SQSTM_HUMAN (1-440): 0: 760: 100.00		AJUBA_HUMAN (86-395): 1.07e-16: 84.3: 12.01
+	Hs
		1107790 SQSTM_HUMAN (1-440): 0: 760: 100.00		PDLI3_HUMAN (398-453): 1.34e-11: 67.6: 30.36
+	Ce
		113309 Q9N3Z0_CAEEL (116-195): 3.79e-33: 126: 32.22		G5EFG1_CAEEL (52-453): 6.09e-52: 187: 24.43
+	Hs
		878499 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		PAXI_HUMAN (196-397): 6.31e-29: 121: 21.76
+	Hs
		253966 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		LPXN_HUMAN (79-397): 1.17e-26: 112: 15.99
+	Hs
		1295532 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		PDLI5_HUMAN (1-269): 1.13e-22: 102: 24.82
+	Ce
		113435 Q9N3Z0_CAEEL (116-195): 3.79e-33: 126: 32.22		G5EFL5_CAEEL (1-338): 4.25e-13: 73.9: 14.08
+	Hs
		1151611 MIB2_HUMAN (106-264): 3.56e-23: 104: 26.09		TRIP6_HUMAN (335-456): 5.98e-17: 84.7: 30.40
+	Hs
		1128730 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		ZYX_HUMAN (74-336): 3.79e-10: 64.2: 13.87