HitPredict

Interactor 1: MTG16 (O75081)
Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4)
Gene: CBFA2T3

Interactor 2: TAL1 (P17542)
T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Class A basic helix-loop-helix protein 17) (bHLHa17) (Stem cell protein) (T-cell leukemia/lymphoma protein 5)
Gene: TAL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	26593974, 16407974, 19497860
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 653 Hs			1 331
+	Mm
		222894 MTG16_MOUSE (22-653): 0: 919: 86.34		TAL1_MOUSE (1-331): 1.7e-77: 242: 93.05
+	Hs
		253962 MTG16_HUMAN (1-653): 0: 1003: 100.00		LYL1_HUMAN (81-312): 1.23e-33: 127: 35.02
+	Hs
		203438 MTG8R_HUMAN (53-641): 0: 841: 57.64		TAL1_HUMAN (1-331): 2.49e-79: 246: 100.00
+	Mm
		250767 MTG8R_MOUSE (56-641): 0: 836: 58.03		TAL1_MOUSE (1-331): 1.7e-77: 242: 93.05
+	Mm
		222897 MTG16_MOUSE (22-653): 0: 919: 86.34		ITF2_MOUSE (51-288): 4.18e-29: 119: 15.79
+	Hs
		987449 MTG8_HUMAN (54-653): 0: 846: 69.67		NGN1_HUMAN (182-301): 2.96e-28: 111: 27.78
+	Hs
		203458 MTG8R_HUMAN (53-641): 0: 841: 57.64		NGN1_HUMAN (182-301): 2.96e-28: 111: 27.78
+	Mm
		140197 MTG8_MOUSE (54-653): 0: 833: 69.67		NDF4_MOUSE (179-323): 2.1e-29: 116: 22.70
+	Hs
		987416 MTG8_HUMAN (54-653): 0: 846: 69.67		TAL2_HUMAN (186-257): 1.02e-26: 103: 72.22
+	Hs
		203451 MTG8R_HUMAN (53-641): 0: 841: 57.64		TAL2_HUMAN (186-257): 1.02e-26: 103: 72.22
+	Mm
		1143187 MTG8_MOUSE (54-653): 0: 833: 69.67		TAL2_MOUSE (186-257): 6.41e-28: 106: 70.83