HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: BRMS1 (Q9HCU9)
Breast cancer metastasis-suppressor 1
Gene: BRMS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 14581478, 28514442, 33961781, 16919237, 26496610, 17000776, 21258344, 23752268
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~Sds3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0030336 - negative regulation of cell migration
and 7 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 482
Hs

1 246
+ Hs
+ Mm
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 11Aug2025