HitPredict

Interactor 1: G5ECY6 (G5ECY6)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CHIP)
Gene: chn-1

Interactor 2: G5EG62 (G5EG62)
UNC-45
Gene: unc-45

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15294159
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0018991 - egg-laying behavior GO:0031625 - ubiquitin protein ligase binding GO:0040011 - locomotion GO:0045214 - sarcomere organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 266 Ce			1 961
+	Hs
		1311241 CHIP_HUMAN (2-257): 6.64e-55: 180: 38.63		UN45B_HUMAN (7-943): 0: 837: 30.76
+	Hs
		1405913 CHIP_HUMAN (2-257): 6.64e-55: 180: 38.63		DNJC7_HUMAN (2-388): 1.33e-42: 165: 11.78
+	Mm
		1221303 PPP5_MOUSE (4-217): 3.33e-36: 136: 18.18		PPP5_MOUSE (5-251): 5.58e-41: 160: 18.88
+	Hs
		916630 PPP5_HUMAN (4-225): 3.3e-36: 136: 18.39		PPP5_HUMAN (5-240): 6.96e-40: 156: 18.91
+	Ps
		1444869 TOC64_PEA (3-117): 1.81e-34: 132: 28.45		TOC64_PEA (6-129): 9.69e-38: 152: 40.32
+	Hs
		731115 PPP5_HUMAN (4-225): 3.3e-36: 136: 18.39		STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57
+	Dm
		1475644 Q9VJD4_DROME (3-189): 4.32e-34: 127: 18.62		Q9VH81_DROME (7-199): 4.46e-37: 149: 19.59
+	Hs
		226714 SGTA_HUMAN (2-121): 4.71e-33: 124: 27.27		STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57
+	Hs
		731614 UN45A_HUMAN (2-208): 4.29e-31: 123: 14.69		STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57
+	Hs
		185549 PPP5_HUMAN (4-225): 3.3e-36: 136: 18.39		OGT1_HUMAN (2-435): 6.96e-28: 123: 10.20
+	Hs
		731618 RPAP3_HUMAN (3-209): 2.92e-28: 114: 17.79		STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57
+	Dm
		1478365 Q9VJD4_DROME (3-189): 4.32e-34: 127: 18.62		Q9VPN5_DROME (5-303): 1.03e-27: 120: 15.74
+	Dm
		1475708 Q9VH81_DROME (3-217): 6.05e-32: 124: 16.02		Q9VPN5_DROME (5-303): 1.03e-27: 120: 15.74
+	Hs
		1153738 UN45A_HUMAN (2-208): 4.29e-31: 123: 14.69		TOM34_HUMAN (6-177): 8.27e-26: 110: 26.74
+	Hs
		1435166 RPAP3_HUMAN (3-209): 2.92e-28: 114: 17.79		RPAP3_HUMAN (2-131): 4.22e-26: 116: 35.39
+	Hs
		730996 STIP1_HUMAN (4-167): 4.64e-18: 85.3: 20.93		STIP1_HUMAN (5-357): 2.44e-35: 144: 12.57
+	Hs
		185466 STIP1_HUMAN (4-167): 4.64e-18: 85.3: 20.93		OGT1_HUMAN (2-435): 6.96e-28: 123: 10.20
+	Hs
		1389486 SGTB_HUMAN (1-158): 9.44e-34: 125: 17.28		SGTB_HUMAN (57-200): 6.66e-13: 72.5: 15.39
+	Hs
		226852 SGTA_HUMAN (2-121): 4.71e-33: 124: 27.27		SGTB_HUMAN (57-200): 6.66e-13: 72.5: 15.39