Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: MEPCE (Q7L2J0)
7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog)
Gene: MEPCE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.751

The method score is based on:

Property Details
Experiments 26725010, 29845934, 33961781, 35271311, 18483487, 17643375, 24778252, 18281698
Identification Methods affinity chromatography technology, pull down, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0097322 - 7SK snRNA binding
GO:0120259 - 7SK snRNP
and 3 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 582
Hs

1 689
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024