HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: CDK15 (Q96Q40)
Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)
Gene: CDK15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 435
+	Hs
		625477 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK2_HUMAN (100-398): 1.05e-141: 408: 47.51
+	Hs
		960098 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK3_HUMAN (100-405): 4.94e-139: 401: 48.38
+	Hs
		300640 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK14_HUMAN (17-427): 3.18e-131: 388: 55.85
+	Hs
		960373 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK16_HUMAN (20-429): 5.02e-131: 388: 44.88
+	Hs
		960440 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK17_HUMAN (17-429): 5.31e-130: 386: 43.57
+	Hs
		414946 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK1_HUMAN (100-391): 1.9e-132: 384: 45.09
+	Hs
		960291 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK5_HUMAN (100-393): 9.34e-131: 380: 50.00
+	Hs
		989681 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		CDK18_HUMAN (44-424): 3.28e-125: 373: 47.77
+	Hs
		403088 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		CDK2_HUMAN (100-398): 1.05e-141: 408: 47.51
+	Hs
		516362 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		CDK2_HUMAN (100-398): 1.05e-141: 408: 47.51
+	Sc
		565522 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		PHO85_YEAST (100-389): 7.77e-131: 381: 50.17
+	Hs
		989704 LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02		CDK18_HUMAN (44-424): 3.28e-125: 373: 47.77
+	Dm
		114975 LARP_DROME (38-120): 1.58e-13: 76.1: 35.23		M9PE01_DROME (8-416): 7.43e-131: 389: 51.20
+	At
		1321248 PABP8_ARATH (2-127): 5.76e-15: 80: 11.91		CDKD2_ARATH (91-432): 8.37e-130: 379: 38.78
+	Hs
		414931 ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50		CDK1_HUMAN (100-391): 1.9e-132: 384: 45.09
+	Sc
		339316 PABP_YEAST (9-243): 8.44e-33: 134: 13.47		CDK1_YEAST (98-387): 2.01e-81: 254: 47.81