HitPredict

Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2221 Hs			1 520
+	Hs
		1119185 CAC1C_HUMAN (1-2221): 0: 1897: 100.00		K2C1B_HUMAN (66-435): 6.32e-126: 381: 56.49
+	Hs
		407446 CAC1C_HUMAN (1-2221): 0: 1897: 100.00		K2C1_HUMAN (76-442): 1.8e-110: 343: 56.95
+	Hs
		876467 CAC1C_HUMAN (1-2221): 0: 1897: 100.00		K2C6C_HUMAN (76-448): 2.41e-83: 270: 59.52
+	Hs
		385270 CAC1C_HUMAN (1-2221): 0: 1897: 100.00		K2C6A_HUMAN (76-448): 2.28e-82: 268: 59.79
+	Hs
		566375 CAC1C_HUMAN (1-2221): 0: 1897: 100.00		K2C5_HUMAN (6-427): 6.97e-82: 267: 51.69
+	Hs
		618139 CAC1C_HUMAN (1-2221): 0: 1897: 100.00		K2C4_HUMAN (6-442): 1.1e-75: 249: 55.22
+	Hs
		437107 SCN4A_HUMAN (4-1754): 0: 1212: 21.72		K2C8_HUMAN (83-465): 4.88e-121: 365: 55.09