Interactor 1: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Interactor 2: PEF1 (Q9UBV8)
Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1)
Gene: PEF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 25416956, 27716508, 30190310, 32296183, 35120648, 16189514, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, enzymatic study, pull down, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0014029 - neural crest formation
GO:0014032 - neural crest cell development
GO:0030127 - COPII vesicle coat
GO:0031463 - Cul3-RING ubiquitin ligase complex
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 568
Hs

1 284
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024