HitPredict

Interactor 1: Q53XM7 (Q53XM7)
VAMP (Vesicle-associated membrane protein)-associated protein B and C (cDNA FLJ13179 fis, clone NT2RP3003918, highly similar to Vesicle-associated membrane protein-associated protein B/C)
Gene: VAPB

Interactor 2: OSBL2 (Q9H1P3)
Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2)
Gene: OSBPL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 243 Hs			1 480
+	Hs
		310803 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBL2_HUMAN (1-480): 0: 601: 100.00
+	Hs
		1328794 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBL2_HUMAN (1-480): 0: 601: 100.00
+	Hs
		310786 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBL1_HUMAN (3-480): 0: 574: 64.52
+	Hs
		1315823 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBL1_HUMAN (3-480): 0: 574: 64.52
+	Hs
		310745 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBP2_HUMAN (1-480): 1.21e-168: 500: 34.80
+	Hs
		310813 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBL3_HUMAN (2-470): 6.41e-166: 492: 36.95
+	Hs
		1282120 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBP2_HUMAN (1-480): 1.21e-168: 500: 34.80
+	Hs
		310792 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBL6_HUMAN (2-470): 3.81e-161: 481: 35.98
+	Hs
		310506 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBP1_HUMAN (2-480): 4.47e-162: 480: 35.96
+	Hs
		1331232 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBL3_HUMAN (2-470): 6.41e-166: 492: 36.95
+	Hs
		1318032 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBL6_HUMAN (2-470): 3.81e-161: 481: 35.98
+	Hs
		603095 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBP1_HUMAN (2-480): 4.47e-162: 480: 35.96
+	Hs
		1318024 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBL7_HUMAN (2-469): 2.08e-154: 461: 34.31
+	Hs
		310768 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBL9_HUMAN (2-471): 5.91e-130: 395: 20.75
+	Hs
		310785 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSB10_HUMAN (24-470): 1.92e-124: 382: 20.21
+	Hs
		1302540 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBL9_HUMAN (2-471): 5.91e-130: 395: 20.75
+	Hs
		310791 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBL8_HUMAN (9-479): 1.08e-120: 375: 23.43
+	Hs
		310784 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSB11_HUMAN (4-470): 4.14e-118: 365: 17.59
+	Hs
		1315200 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSB10_HUMAN (24-470): 1.92e-124: 382: 20.21
+	Hs
		1315187 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSB11_HUMAN (4-470): 4.14e-118: 365: 17.59