HitPredict

Interactor 1: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Interactor 2: KCJ12 (Q14500)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: KCNJ12

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	24550280, 30126976
Identification Methods	phage display, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1655 Hs			1 433
+	Hs
		993074 SCRIB_HUMAN (1-1655): 0: 940: 100.00		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Hs
		870031 SCRIB_HUMAN (1-1655): 0: 940: 100.00		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		1006064 DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Rn
		723865 DLG4_RAT (812-1187): 5.61e-49: 189: 22.42		KCJ12_RAT (1-433): 0: 726: 95.84
+	Hs
		993069 DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Hs
		1127300 DLG3_HUMAN (724-947): 1.79e-19: 97.4: 31.23		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		1127299 DLG2_HUMAN (591-851): 2.07e-16: 87.5: 16.79		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Rn
		909973 DLG1_RAT (955-1182): 3.1e-24: 112: 37.56		KCJ12_RAT (1-433): 0: 726: 95.84
+	Rn
		909976 DLG2_RAT (816-1021): 6.73e-21: 101: 22.33		KCJ12_RAT (1-433): 0: 726: 95.84
+	Rn
		909975 DLG3_RAT (724-947): 3.66e-19: 96.3: 31.23		KCJ12_RAT (1-433): 0: 726: 95.84
+	Mm
		909979 DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42		KCNJ4_MOUSE (32-433): 0: 616: 63.64
+	Rn
		1224263 DLG1_RAT (955-1182): 3.1e-24: 112: 37.56		KCNJ2_RAT (6-433): 0: 682: 70.93
+	Hs
		870028 DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Mm
		1223762 DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42		Q9QYK8_MOUSE (39-427): 0: 600: 63.85
+	Rn
		1224609 DLG2_RAT (816-1021): 6.73e-21: 101: 22.33		KCNJ2_RAT (6-433): 0: 682: 70.93
+	Hs
		870032 DLG2_HUMAN (591-851): 2.07e-16: 87.5: 16.79		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		870072 LRRC1_HUMAN (1-189): 8.84e-41: 161: 27.51		KCNJ6_HUMAN (40-381): 0: 527: 52.92
+	Mm
		312067 DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42		KCNJ1_MOUSE (39-358): 1.55e-172: 489: 49.85
+	Mm
		1223790 DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42		KCJ16_MOUSE (36-363): 2.85e-163: 467: 49.39
+	Mm
		1223754 DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42		KCJ10_MOUSE (42-354): 1.53e-159: 456: 44.76