HitPredict

Interactor 1: KCNJ4 (P48050)
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene: KCNJ4

Interactor 2: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11997254
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 870
+	Hs
		1127299 KCJ12_HUMAN (7-445): 0: 662: 63.86		DLG2_HUMAN (1-870): 0: 732: 100.00
+	Rn
		909976 KCJ12_RAT (7-445): 0: 649: 63.55		DLG2_RAT (1-870): 0: 718: 94.94
+	Rn
		1224609 KCNJ2_RAT (7-445): 0: 642: 60.91		DLG2_RAT (1-870): 0: 718: 94.94
+	Hs
		870029 KCNJ4_HUMAN (1-445): 0: 691: 100.00		DLG1_HUMAN (7-870): 8.32e-166: 507: 52.11
+	Hs
		1091492 KCJ12_HUMAN (7-445): 0: 662: 63.86		DLG1_HUMAN (7-870): 8.32e-166: 507: 52.11
+	Hs
		84402 KCJ18_HUMAN (7-445): 0: 656: 63.41		DLG1_HUMAN (7-870): 8.32e-166: 507: 52.11
+	Rn
		909973 KCJ12_RAT (7-445): 0: 649: 63.55		DLG1_RAT (9-870): 2.17e-166: 508: 51.65
+	Rn
		1224263 KCNJ2_RAT (7-445): 0: 642: 60.91		DLG1_RAT (9-870): 2.17e-166: 508: 51.65
+	Hs
		870028 KCNJ4_HUMAN (1-445): 0: 691: 100.00		DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52
+	Mm
		909979 KCNJ4_MOUSE (1-445): 0: 692: 96.86		DLG4_MOUSE (13-446): 2.95e-30: 129: 16.52
+	Hs
		168652 KCNJ4_HUMAN (1-445): 0: 691: 100.00		CSKP_HUMAN (6-307): 2.26e-24: 111: 10.54
+	Hs
		1006064 KCJ12_HUMAN (7-445): 0: 662: 63.86		DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52
+	Hs
		1127300 KCJ12_HUMAN (7-445): 0: 662: 63.86		DLG3_HUMAN (11-444): 5.43e-30: 129: 15.08
+	Mm
		1223762 Q9QYK8_MOUSE (9-439): 0: 658: 97.45		DLG4_MOUSE (13-446): 2.95e-30: 129: 16.52
+	Rn
		723865 KCJ12_RAT (7-445): 0: 649: 63.55		DLG4_RAT (13-446): 5.09e-30: 129: 16.52
+	Hs
		168690 KCJ12_HUMAN (7-445): 0: 662: 63.86		CSKP_HUMAN (6-307): 2.26e-24: 111: 10.54
+	Hs
		993069 KCNJ2_HUMAN (7-445): 0: 641: 60.46		DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52
+	Rn
		909974 KCJ12_RAT (7-445): 0: 649: 63.55		CSKP_RAT (6-448): 1.05e-25: 116: 9.40
+	Hs
		1127305 KCJ12_HUMAN (7-445): 0: 662: 63.86		PALS2_HUMAN (12-233): 2.28e-19: 94.9: 15.92
+	Rn
		909975 KCJ12_RAT (7-445): 0: 649: 63.55		DLG3_RAT (270-492): 1.6e-12: 73.7: 16.59