HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: SRBS1 (Q9BX66)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: SORBS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1292
+	Hs
		909544 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SPTN1_HUMAN (304-902): 8.17e-59: 225: 13.39
+	Sp
		788710 RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77		CDC15_SCHPO (223-850): 1.14e-66: 246: 16.33
+	Hs
		909706 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DNMBP_HUMAN (796-1253): 2.23e-17: 90.7: 14.23
+	Mm
		910242 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		SRBS2_MOUSE (508-926): 2.95e-15: 83.3: 15.18
+	Hs
		298967 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SRBS2_HUMAN (516-926): 8.23e-14: 78.7: 14.74
+	Hs
		299007 V9HW98_HUMAN (1-255): 4.87e-154: 430: 100.00		SRBS2_HUMAN (516-926): 8.23e-14: 78.7: 14.74
+	Hs
		909849 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SH3R3_HUMAN (407-924): 1.49e-12: 74.3: 10.82
+	Hs
		909634 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SH319_HUMAN (793-851): 9.71e-11: 68.4: 37.29
+	Hs
		909744 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SH3R1_HUMAN (220-850): 8.23e-10: 65.6: 13.22