Interactor 1: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2
Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.86 | 1.00 | 0.930 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 12473661, 33961781, 40437099, 16628223 |
| Identification Methods | affinity chromatography technology, two hybrid, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~Ank_2, Ank_2~ArfGap, Ank_2~GIT_SHD, ArfGap~ArfGap, ArfGap~GIT_SHD, GIT1_C~GIT1_C, GIT_CC~GIT_CC, GIT_SHD~GIT_SHD |
| Common GO terms | GO:0005096 - GTPase activator activity GO:0005925 - focal adhesion GO:0007420 - brain development GO:0008270 - zinc ion binding GO:0008277 - regulation of G protein-coupled receptor signaling pathway and 4 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
