HitPredict

Interactor 1: Q5S3G3 (Q5S3G3)
HLA class I histocompatibility antigen A alpha chain (MHC class I antigen)
Gene: HLA-A

Interactor 2: LIRB2 (Q8N423)
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)
Gene: LILRB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	24018270, 12853576
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~ig, C1-set~Ig_2, MHC_I~ig
Common GO terms	GO:0005615 - extracellular space GO:0006955 - immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Hs			1 597
+	Hs
		1232786 Q95J06_HUMAN (1-365): 0: 511: 92.06		LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00
+	Hs
		382478 HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08		LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00
+	Hs
		1245576 Q95J06_HUMAN (1-365): 0: 511: 92.06		LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92
+	Hs
		382485 HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08		LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92
+	Hs
		1130838 Q5S3G3_HUMAN (1-365): 1.47e-178: 501: 100.00		LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92
+	Hs
		1060406 Q95J06_HUMAN (1-365): 0: 511: 92.06		KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93
+	Hs
		382420 HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08		KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93
+	Hs
		1060403 Q5SUL5_HUMAN (1-365): 3.17e-176: 495: 96.99		KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93
+	Hs
		382484 HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08		LIRB4_HUMAN (1-238): 2.36e-57: 200: 48.32
+	Hs
		798280 Q5S3G3_HUMAN (1-365): 1.47e-178: 501: 100.00		KI2S4_HUMAN (119-337): 4.16e-51: 180: 41.82
+	Hs
		798148 Q5RIP0_HUMAN (1-364): 1.63e-165: 468: 83.29		KI2L1_HUMAN (117-337): 5.21e-48: 173: 40.54
+	Hs
		798146 Q5D1W8_HUMAN (1-364): 1.54e-163: 463: 83.01		KI2L1_HUMAN (117-337): 5.21e-48: 173: 40.54
+	Hs
		798195 Q5S3G3_HUMAN (1-365): 1.47e-178: 501: 100.00		KI2L3_HUMAN (117-334): 1.26e-29: 121: 40.18
+	Hs
		47499 HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08		A0A8I5QEB2_HUMAN (317-447): 2.68e-18: 89.3: 32.06
+	Hs
		798194 Q5RIP0_HUMAN (1-364): 1.63e-165: 468: 83.29		KI2L3_HUMAN (117-334): 1.26e-29: 121: 40.18
+	Hs
		798173 Q5RIP0_HUMAN (1-364): 1.63e-165: 468: 83.29		KI2L2_HUMAN (117-334): 7.81e-29: 119: 39.09
+	Hs
		382341 HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08		KI3L2_HUMAN (323-597): 2.69e-16: 83.5: 20.19
+	Hs
		798244 Q5S3G3_HUMAN (1-365): 1.47e-178: 501: 100.00		KI3L2_HUMAN (323-597): 2.69e-16: 83.5: 20.19
+	Hs
		798190 Q5D1W8_HUMAN (1-364): 1.54e-163: 463: 83.01		KI2L3_HUMAN (117-334): 1.26e-29: 121: 40.18
+	Hs
		798171 Q5D1W8_HUMAN (1-364): 1.54e-163: 463: 83.01		KI2L2_HUMAN (117-334): 7.81e-29: 119: 39.09