HitPredict

Interactor 1: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Interactor 2: SHC4 (Q6S5L8)
SHC-transforming protein 4 (Rai-like protein) (RaLP) (SHC-transforming protein D) (hShcD) (Src homology 2 domain-containing-transforming protein C4) (SH2 domain protein C4)
Gene: SHC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36574265
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 630
+	Hs
		1137901 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		SHC3_HUMAN (24-621): 3.6e-145: 435: 42.88
+	Hs
		711257 MYH10_HUMAN (2-508): 2.51e-19: 94.9: 10.53		SHC1_HUMAN (26-620): 3.38e-155: 461: 45.40
+	Hs
		711258 MYH11_HUMAN (103-571): 3.81e-18: 91.5: 13.36		SHC1_HUMAN (26-620): 3.38e-155: 461: 45.40
+	Hs
		711256 MYH9_HUMAN (263-570): 8.04e-10: 64.5: 13.64		SHC1_HUMAN (26-620): 3.38e-155: 461: 45.40
+	Hs
		294860 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		BCAR3_HUMAN (375-619): 1.73e-41: 163: 19.25
+	Hs
		699753 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		P85A_HUMAN (521-622): 5.05e-20: 96.7: 25.47
+	Mm
		1296766 ITSN1_MOUSE (27-390): 4.11e-14: 78.1: 12.43		ANS1B_MOUSE (64-385): 7.27e-52: 195: 16.51
+	Hs
		355117 MRCKB_HUMAN (222-542): 6.54e-12: 71.2: 14.68		APBA3_HUMAN (20-354): 1.81e-54: 197: 15.83
+	Hs
		563066 MYH8_HUMAN (2-454): 1.71e-18: 92.2: 13.13		SHD_HUMAN (349-617): 2.06e-44: 163: 15.52
+	Hs
		556946 MYH7_HUMAN (2-460): 8.98e-18: 89.9: 10.81		SHD_HUMAN (349-617): 2.06e-44: 163: 15.52
+	Hs
		557552 MYH4_HUMAN (7-434): 1.49e-13: 76.5: 12.96		SRC_HUMAN (385-628): 1.61e-43: 165: 14.77
+	Hs
		117127 MYH9_HUMAN (263-570): 8.04e-10: 64.5: 13.64		J3QRU1_HUMAN (367-628): 1.23e-43: 166: 16.12
+	Hs
		463006 MYH9_HUMAN (263-570): 8.04e-10: 64.5: 13.64		YES_HUMAN (367-628): 1.09e-43: 166: 16.12
+	Hs
		699767 ITSN1_HUMAN (92-469): 4.68e-14: 78.1: 11.00		P85A_HUMAN (521-622): 5.05e-20: 96.7: 25.47
+	Hs
		773152 MYH10_HUMAN (2-508): 2.51e-19: 94.9: 10.53		GRB2_HUMAN (520-616): 5.13e-14: 73.4: 30.48
+	Hs
		776799 MYH11_HUMAN (103-571): 3.81e-18: 91.5: 13.36		GRB2_HUMAN (520-616): 5.13e-14: 73.4: 30.48
+	Hs
		772723 MYH9_HUMAN (263-570): 8.04e-10: 64.5: 13.64		GRB2_HUMAN (520-616): 5.13e-14: 73.4: 30.48