HitPredict

Interactor 1: MRCKA (Q5VT25)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPA

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1732 Hs			1 494
+	Hs
		858688 MRCKB_HUMAN (1-1731): 0: 1417: 60.38		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		609690 KAPCG_HUMAN (43-378): 8.53e-126: 399: 32.46		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		1305109 LATS2_HUMAN (65-376): 3.53e-75: 275: 41.23		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		149293 CTRO_HUMAN (4-1044): 3.09e-128: 447: 24.43		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Rn
		858690 AKT3_RAT (13-404): 7.21e-133: 424: 31.76		PPP5_RAT (26-166): 3.94e-16: 82.8: 28.37
+	Hs
		609649 KAPCG_HUMAN (43-378): 8.53e-126: 399: 32.46		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Rn
		193486 AKT3_RAT (13-404): 7.21e-133: 424: 31.76		STIP1_RAT (8-208): 3.19e-12: 70.7: 12.34
+	Hs
		609697 KAPCG_HUMAN (43-378): 8.53e-126: 399: 32.46		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		609656 KAPCG_HUMAN (43-378): 8.53e-126: 399: 32.46		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		858673 LATS2_HUMAN (65-376): 3.53e-75: 275: 41.23		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79