HitPredict

Interactor 1: EEA1 (Q15075)
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)
Gene: EEA1

Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042803 - protein homodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1411 Hs			1 8797
+	Hs
		1141827 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		SYNE2_HUMAN (13-6897): 9.14e-141: 503: 12.40
+	Hs
		1040295 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		DYST_HUMAN (6586-8703): 3.47e-45: 186: 11.34
+	Hs
		1028773 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		SPTB2_HUMAN (128-2193): 3.44e-26: 123: 9.82
+	Hs
		1117368 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		SPTN1_HUMAN (7955-8728): 7.67e-25: 118: 13.61
+	Hs
		1142023 EEA1_HUMAN (1-1411): 5.51e-125: 424: 100.00		MACF1_HUMAN (215-1305): 9.44e-13: 78.7: 10.86
+	Hs
		1040365 CP250_HUMAN (311-1410): 7.38e-38: 158: 12.73		DYST_HUMAN (6586-8703): 3.47e-45: 186: 11.34
+	Hs
		174713 MYH9_HUMAN (1090-1400): 4.43e-13: 76.8: 14.79		SPTN2_HUMAN (18-355): 7.97e-49: 197: 39.12
+	Hs
		772814 MYH9_HUMAN (1090-1400): 4.43e-13: 76.8: 14.79		PLEC_HUMAN (257-2187): 1.43e-45: 187: 7.68
+	Hs
		156700 CTRO_HUMAN (563-1338): 6.27e-10: 66.2: 19.09		SPTN2_HUMAN (18-355): 7.97e-49: 197: 39.12
+	Hs
		772753 MYH9_HUMAN (1090-1400): 4.43e-13: 76.8: 14.79		DYST_HUMAN (6586-8703): 3.47e-45: 186: 11.34
+	Mm
		98081 DESP_MOUSE (566-1340): 7.63e-14: 79.3: 19.93		PLEC_MOUSE (6789-8770): 2.94e-41: 173: 10.09
+	Hs
		556923 MYH7_HUMAN (1-591): 3.62e-26: 119: 12.80		SPTN1_HUMAN (7955-8728): 7.67e-25: 118: 13.61
+	Mm
		1037844 MYH6_MOUSE (1-565): 1.58e-25: 117: 11.77		DYST_MOUSE (7457-8766): 3.04e-14: 83.8: 10.98
+	Hs
		772748 MYH9_HUMAN (1090-1400): 4.43e-13: 76.8: 14.79		SPTB2_HUMAN (128-2193): 3.44e-26: 123: 9.82
+	Hs
		772789 MYH9_HUMAN (1090-1400): 4.43e-13: 76.8: 14.79		SPTN1_HUMAN (7955-8728): 7.67e-25: 118: 13.61
+	Hs
		157250 CTRO_HUMAN (563-1338): 6.27e-10: 66.2: 19.09		SPTB2_HUMAN (128-2193): 3.44e-26: 123: 9.82
+	Hs
		157346 CTRO_HUMAN (563-1338): 6.27e-10: 66.2: 19.09		SPTN1_HUMAN (7955-8728): 7.67e-25: 118: 13.61
+	Hs
		773085 MYH9_HUMAN (1090-1400): 4.43e-13: 76.8: 14.79		MACF1_HUMAN (215-1305): 9.44e-13: 78.7: 10.86
+	Hs
		116295 MYH9_HUMAN (1090-1400): 4.43e-13: 76.8: 14.79		H3BPE1_HUMAN (215-1305): 1.9e-11: 74.5: 10.80
+	Hs
		156889 CTRO_HUMAN (563-1338): 6.27e-10: 66.2: 19.09		SPTB1_HUMAN (7882-8738): 6.19e-14: 82.6: 12.93