HitPredict

Interactor 1: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Interactor 2: RUVB2 (Q9WTM5)
RuvB-like 2 (EC 3.6.4.12) (p47 protein)
Gene: Ruvbl2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005829 - cytosol GO:0090090 - negative regulation of canonical Wnt signaling pathway
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 319 Mm			1 463
+	Mm
		818777 SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43		RUVB2_MOUSE (1-463): 0: 721: 100.00
+	Hs
		818621 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		RUVB2_HUMAN (1-463): 0: 719: 99.57
+	Mm
		888064 Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00		RUVB1_MOUSE (8-451): 0: 658: 42.67
+	Mm
		818680 SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43		RUVB1_MOUSE (8-451): 0: 658: 42.67
+	Hs
		1301006 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		RUVB2_HUMAN (1-463): 0: 719: 99.57
+	Hs
		818624 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		RUVB1_HUMAN (8-451): 0: 658: 42.67
+	Hs
		1301007 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		RUVB1_HUMAN (8-451): 0: 658: 42.67