HitPredict

Interactor 1: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Interactor 2: Q9JM08 (Q9JM08)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 319 Mm			1 428
+	Hs
		177229 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		HDAC3_HUMAN (1-428): 0: 606: 99.07
+	Mm
		140273 Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00		HDAC1_MOUSE (3-385): 0: 587: 62.66
+	Mm
		140241 SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43		HDAC1_MOUSE (3-385): 0: 587: 62.66
+	Hs
		818023 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Mm
		936399 Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00		HDAC2_MOUSE (3-422): 0: 576: 58.16
+	Hs
		818314 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		HDAC2_HUMAN (3-422): 0: 578: 58.39
+	Mm
		818688 SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43		HDAC2_MOUSE (3-422): 0: 576: 58.16
+	Hs
		177214 SOX6_HUMAN (18-202): 1.01e-33: 132: 29.73		HDAC3_HUMAN (1-428): 0: 606: 99.07
+	Hs
		1038645 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		1270390 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		HDAC2_HUMAN (3-422): 0: 578: 58.39
+	Hs
		727863 SOX6_HUMAN (18-202): 1.01e-33: 132: 29.73		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		1038578 BBX_HUMAN (31-257): 3.4e-33: 131: 20.78		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		883315 SOX8_HUMAN (12-312): 3.61e-33: 128: 26.23		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		727903 SOX6_HUMAN (18-202): 1.01e-33: 132: 29.73		HDAC2_HUMAN (3-422): 0: 578: 58.39
+	Mm
		140296 NSD2_MOUSE (4-250): 6.03e-29: 119: 10.32		HDAC1_MOUSE (3-385): 0: 587: 62.66
+	Hs
		297491 TOX4_HUMAN (9-316): 7.19e-28: 115: 12.14		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		331809 NSD2_HUMAN (1-250): 1.25e-27: 115: 11.83		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		1038764 HM20B_HUMAN (6-159): 4.8e-28: 112: 23.38		HDAC1_HUMAN (3-385): 0: 587: 62.66
+	Hs
		331858 NSD2_HUMAN (1-250): 1.25e-27: 115: 11.83		HDAC2_HUMAN (3-422): 0: 578: 58.39
+	Hs
		1270484 HM20B_HUMAN (6-159): 4.8e-28: 112: 23.38		HDAC2_HUMAN (3-422): 0: 578: 58.39