Interactor 1: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1
Interactor 2: RRAGA (Q7L523)
Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1)
Gene: RRAGA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.962 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 34079125, 33961781, 31601708, 21816923, 25567906, 22980980, 25561175 |
| Identification Methods | proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Gtr1_RagA~LAMTOR |
| Common GO terms | GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0008104 - protein localization GO:0031669 - cellular response to nutrient levels GO:0032008 - positive regulation of TOR signaling and 5 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
