HitPredict

Interactor 1: HERC1 (Q15751)
Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619)
Gene: HERC1

Interactor 2: S27A4 (Q6P1M0)
Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-)
Gene: SLC27A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 4861 Hs			1 643
+	Hs
		1153176 HERC1_HUMAN (1-4861): 0: 6690: 100.00		S27A1_HUMAN (4-643): 0: 603: 61.68
+	Hs
		1243618 HUWE1_HUMAN (4372-4842): 1.37e-132: 474: 21.86		S27A1_HUMAN (4-643): 0: 603: 61.68
+	Sc
		794117 RSP5_YEAST (4360-4843): 6.08e-154: 503: 20.40		FAT2_YEAST (89-603): 2.41e-117: 362: 20.15
+	Hs
		171473 HECD3_HUMAN (4504-4843): 2.8e-52: 203: 36.72		S27A2_HUMAN (46-643): 1.84e-178: 522: 38.74
+	Hs
		342920 HERC2_HUMAN (4282-4427): 9.43e-11: 71.3: 19.73		S27A4_HUMAN (1-643): 0: 646: 100.00
+	Hs
		1207863 HECD3_HUMAN (4504-4843): 2.8e-52: 203: 36.72		S27A3_HUMAN (75-643): 6.24e-157: 469: 37.98
+	Hs
		1369273 RPGR_HUMAN (368-583): 3.2e-14: 82: 28.25		S27A6_HUMAN (13-643): 6.31e-172: 505: 38.33
+	Hs
		1204552 HERC4_HUMAN (4513-4836): 5.34e-12: 75.1: 24.77		S27A6_HUMAN (13-643): 6.31e-172: 505: 38.33
+	Hs
		343115 HERC2_HUMAN (4282-4427): 9.43e-11: 71.3: 19.73		S27A6_HUMAN (13-643): 6.31e-172: 505: 38.33
+	Hs
		1138990 HERC3_HUMAN (602-747): 3.18e-10: 68.9: 30.82		S27A6_HUMAN (13-643): 6.31e-172: 505: 38.33