Protein: RPGR
X-linked retinitis pigmentosa GTPase regulator

Gene: RPGR
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q92834

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0003723 - RNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1369257

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

6

9

Small-scale

0.743

High

1228444

FTM
Protein fantom

5

9

High-throughput

0.718

High

273357

NPHP4
Nephrocystin-4

5

2

Small-scale

0.714

High

231402

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

6

0

Small-scale

0.711

High

184311

NPHP1
Nephrocystin-1

3

1

Small-scale

0.667

High

575176

IDE
Insulin-degrading enzyme

2

4

High-throughput

0.628

High

1112376

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

2

1

High-throughput

0.628

High

1369263

TBB1
Tubulin beta-1 chain

2

11

High-throughput

0.628

High

1104360

ORC2
Origin recognition complex subunit 2

2

0

High-throughput

0.602

High

1369269

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

2

0

High-throughput

0.602

High

665125

COT2
COUP transcription factor 2

2

4

High-throughput

0.574

High

1116943

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

2

1

High-throughput

0.574

High

1245006

SPSB3
SPRY domain-containing SOCS box protein 3

2

12

High-throughput

0.574

High

1369265

PDLI7
PDZ and LIM domain protein 7

2

1

High-throughput

0.574

High

1130132

SMC1A
Structural maintenance of chromosomes protein 1A

1

3

Small-scale

0.561

High

719358

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.536

High

1272512

CSN6
COP9 signalosome complex subunit 6

1

3

High-throughput

0.536

High

1369266

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

1

High-throughput

0.536

High

1123743

DCTN1
Dynactin subunit 1

1

2

High-throughput

0.515

High

1369271

SMC3
Structural maintenance of chromosomes protein 3

1

3

Small-scale

0.512

High

177030

CE290
Centrosomal protein of 290 kDa

1

13

Small-scale

0.479

High

375801

RASK
GTPase KRas

1

1

High-throughput

0.479

High

408121

TBB4A
Tubulin beta-4A chain

1

7

High-throughput

0.479

High

457596

TBB5
Tubulin beta chain

1

7

High-throughput

0.479

High

727906

DNJA1
DnaJ homolog subfamily A member 1

1

3

High-throughput

0.479

High

896843

DYN2
Dynamin-2

1

2

High-throughput

0.479

High

909122

NEK4
Serine/threonine-protein kinase Nek4

1

9

High-throughput

0.479

High

997451

TBB4B
Tubulin beta-4B chain

1

7

High-throughput

0.479

High

1038676

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

7

High-throughput

0.479

High

1071178

ARL16
ADP-ribosylation factor-like protein 16

1

3

High-throughput

0.479

High

1140122

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

Small-scale

0.479

High

1259394

TBA1A
Tubulin alpha-1A chain

1

7

High-throughput

0.479

High

1308566

NUDC3
NudC domain-containing protein 3

1

13

High-throughput

0.479

High

1358075

NUDC2
NudC domain-containing protein 2

1

13

High-throughput

0.479

High

1369258

DNJC7
DnaJ homolog subfamily C member 7

1

12

High-throughput

0.479

High

1369259

TBA1C
Tubulin alpha-1C chain

1

8

High-throughput

0.479

High

1369260

TBB2B
Tubulin beta-2B chain

1

7

High-throughput

0.479

High

1369262

UN45A
Protein unc-45 homolog A

1

11

High-throughput

0.479

High

1369264

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

19

High-throughput

0.479

High

1369267

SPAT7
Spermatogenesis-associated protein 7

1

1

Small-scale

0.479

High

1369272

NUDC
Nuclear migration protein nudC

1

13

High-throughput

0.479

High

76561

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

3

High-throughput

0.437

High

962344

RHOA
Transforming protein RhoA

1

6

High-throughput

0.437

High

1141841

EEA1
Early endosome antigen 1

1

6

High-throughput

0.437

High

1369270

TTF2
Transcription termination factor 2

1

3

High-throughput

0.437

High

1369273

S27A6
Long-chain fatty acid transport protein 6

1

7

High-throughput

0.407

High

1369261

HYCCI
Hyccin

2

0

High-throughput

0.328

High

1369268

ORC3
Origin recognition complex subunit 3

2

0

High-throughput

0.328

High

1311761

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.282

High

1233397

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025