HitPredict

Interactor 1: STYK1 (Q6J9G0)
Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)
Gene: STYK1

Interactor 2: DLG5 (Q8TDM6)
Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)
Gene: DLG5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 422 Hs			1 1919
+	Hs
		508118 FGFR1_HUMAN (11-417): 2.76e-127: 388: 24.20		DLG5_HUMAN (1-1919): 0: 936: 100.00
+	Hs
		601553 FGFR2_HUMAN (29-417): 7.84e-125: 382: 23.64		DLG5_HUMAN (1-1919): 0: 936: 100.00
+	Hs
		665293 EPHA2_HUMAN (46-411): 2.25e-121: 377: 21.95		DLG5_HUMAN (1-1919): 0: 936: 100.00
+	Hs
		608056 FGFR4_HUMAN (80-392): 2.13e-119: 367: 28.79		DLG5_HUMAN (1-1919): 0: 936: 100.00
+	Hs
		872433 EPHA5_HUMAN (2-408): 4.94e-121: 377: 20.33		DLG1_HUMAN (1057-1916): 2.05e-154: 501: 19.62
+	Hs
		1021499 EPHA7_HUMAN (36-414): 1.44e-120: 375: 19.37		DLG1_HUMAN (1057-1916): 2.05e-154: 501: 19.62
+	Hs
		872639 EPHA4_HUMAN (42-417): 8.52e-119: 370: 18.73		DLG1_HUMAN (1057-1916): 2.05e-154: 501: 19.62
+	Mm
		403445 SRC_MOUSE (90-390): 9.29e-110: 334: 28.95		DLG4_MOUSE (1177-1916): 2.2e-156: 500: 20.46
+	Hs
		412128 FYN_HUMAN (92-390): 1.01e-109: 334: 28.33		DLG4_HUMAN (1177-1916): 3.58e-156: 499: 20.46
+	Hs
		508052 FGFR1_HUMAN (11-417): 2.76e-127: 388: 24.20		MPP7_HUMAN (1465-1915): 4.41e-107: 356: 20.37
+	Hs
		1072518 EPHA7_HUMAN (36-414): 1.44e-120: 375: 19.37		MPP7_HUMAN (1465-1915): 4.41e-107: 356: 20.37
+	Hs
		609417 FGFR3_HUMAN (10-409): 1.6e-125: 383: 27.01		PALS1_HUMAN (1501-1916): 9.35e-98: 333: 19.50
+	Rn
		73322 SRC_RAT (90-390): 9.56e-110: 334: 28.95		PALS1_RAT (1501-1916): 4.56e-99: 337: 19.50
+	Hs
		522978 SRC_HUMAN (90-390): 1.63e-110: 336: 28.95		MPP2_HUMAN (1419-1919): 2.72e-96: 325: 13.41
+	Hs
		280018 FGFR3_HUMAN (10-409): 1.6e-125: 383: 27.01		MPDZ_HUMAN (1405-1909): 9.74e-18: 92.7: 11.22
+	Ce
		371317 ABL1_CAEEL (143-386): 5.74e-36: 142: 35.74		Q20398_CAEEL (424-794): 5.78e-78: 284: 21.45
+	Hs
		782833 CSK_HUMAN (144-386): 2.31e-36: 140: 36.89		ZO2_HUMAN (1470-1802): 2.6e-11: 71.2: 13.01
+	Hs
		782779 CSK_HUMAN (144-386): 2.31e-36: 140: 36.89		ZO1_HUMAN (698-816): 3.52e-09: 64.5: 16.81