Interactor 1: STK11 (Q15831)
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)
Gene: STK11

Interactor 2: BRSK2 (Q8IWQ3)
Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)
Gene: BRSK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25728766
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains KA1_BRSK~Pkinase, Pkinase~Pkinase, Pkinase~UBA_BRSK
Common GO terms GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005813 - centrosome
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 433
Hs

1 736
+ Rn
+ Hs
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Hs
+ At
+ At
+ At
+ Mm
+ Hs
+ Hs
+ At
+ Zm
+ At
+ Dm
+ Hs

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Last updated: 11Aug2025