HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: MTF2 (Q9Y483)
Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (hPCl2)
Gene: MTF2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	27705803, 24981860, 26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035098 - ESC/E(Z) complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 593
+	Hs
		1158871 RBBP7_HUMAN (1-425): 1.15e-117: 351: 100.00		PHF19_HUMAN (17-591): 0: 728: 45.33
+	Hs
		1066557 RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72		MTF2_HUMAN (1-593): 0: 864: 100.00
+	Mm
		1036630 RBBP4_MOUSE (1-209): 1.71e-39: 148: 12.72		MTF2_MOUSE (1-593): 0: 863: 97.64
+	Hs
		210286 RBBP7_HUMAN (1-425): 1.15e-117: 351: 100.00		PHF1_HUMAN (42-589): 0: 640: 39.01
+	Hs
		1066341 RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72		PHF19_HUMAN (17-591): 0: 728: 45.33
+	Hs
		210266 RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72		PHF1_HUMAN (42-589): 0: 640: 39.01
+	Dm
		1174282 CAF1_DROME (1-209): 1.01e-40: 151: 13.16		PCL_DROME (50-401): 5.13e-133: 416: 31.10
+	Hs
		284983 TAF5L_HUMAN (20-335): 5.98e-51: 182: 19.33		CSR2B_HUMAN (207-550): 1.21e-91: 300: 21.27
+	Dm
		1375063 WDS_DROME (212-422): 1.16e-43: 158: 19.91		ASH2_DROME (190-488): 4.42e-70: 237: 16.19
+	Mm
		965400 WDR5_MOUSE (311-425): 1.4e-17: 85.2: 22.61		CSR2B_MOUSE (207-533): 2.33e-92: 302: 21.51
+	Hs
		965248 WDR5_HUMAN (311-425): 1.4e-17: 85.2: 22.61		CSR2B_HUMAN (207-550): 1.21e-91: 300: 21.27
+	Dm
		1463911 WDS_DROME (212-422): 1.16e-43: 158: 19.91		Q9VJ73_DROME (190-438): 1.26e-62: 222: 16.45
+	Hs
		1291948 WDR5B_HUMAN (218-422): 9.09e-42: 152: 21.46		ASH2L_HUMAN (192-509): 3.77e-48: 179: 12.95
+	Hs
		965302 WDR5_HUMAN (311-425): 1.4e-17: 85.2: 22.61		ASH2L_HUMAN (192-509): 3.77e-48: 179: 12.95