HitPredict

Interactor 1: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Interactor 2: HOME2 (Q9NSB8)
Homer protein homolog 2 (Homer-2) (Cupidin)
Gene: HOMER2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0014069 - postsynaptic density GO:0030425 - dendrite GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 649 Hs			1 354
+	Hs
		1160772 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		HOME3_HUMAN (3-352): 3.09e-56: 189: 44.63
+	Hs
		1160679 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		HOME1_HUMAN (1-350): 3.63e-55: 185: 51.14
+	Hs
		1295226 DBNL_HUMAN (3-464): 9.9e-75: 248: 29.98		HOME1_HUMAN (1-350): 3.63e-55: 185: 51.14
+	Hs
		896538 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		VASP_HUMAN (1-156): 8.51e-18: 85.4: 24.07
+	Hs
		839771 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		EPS15_HUMAN (53-251): 1.19e-09: 61.9: 16.08
+	Rn
		1205551 SYNJ1_RAT (126-645): 5.12e-38: 153: 10.69		Q5JC29_RAT (227-353): 3.69e-09: 60.3: 21.37
+	Hs
		215909 SYNJ1_HUMAN (126-645): 3.15e-29: 126: 9.77		VASP_HUMAN (1-156): 8.51e-18: 85.4: 24.07
+	Hs
		587751 TITIN_HUMAN (184-598): 2.53e-09: 62.9: 10.29		DESP_HUMAN (53-353): 2.2e-31: 127: 18.42