HitPredict

Interactor 1: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 974 Hs			1 543
+	Hs
		573322 WDR59_HUMAN (1-974): 0: 805: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		1083362 RBBP7_HUMAN (43-334): 3.53e-61: 216: 20.46		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		903467 WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1202777 WDR5B_HUMAN (180-476): 5.68e-43: 161: 13.40		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		197078 PRP4_HUMAN (2-175): 7.43e-33: 136: 12.85		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		821227 RBBP7_HUMAN (43-334): 3.53e-61: 216: 20.46		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573279 RBBP7_HUMAN (43-334): 3.53e-61: 216: 20.46		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826601 WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826748 WDR5B_HUMAN (180-476): 5.68e-43: 161: 13.40		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821152 WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		196973 PRP4_HUMAN (2-175): 7.43e-33: 136: 12.85		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573201 WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573346 WDR5B_HUMAN (180-476): 5.68e-43: 161: 13.40		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		196971 PRP4_HUMAN (2-175): 7.43e-33: 136: 12.85		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		196954 PRP4_HUMAN (2-175): 7.43e-33: 136: 12.85		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843214 RBBP7_HUMAN (43-334): 3.53e-61: 216: 20.46		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	At
		186921 MSI1_ARATH (37-321): 7.06e-54: 195: 19.94		TCPA_ARATH (14-521): 1.16e-93: 298: 36.67
+	Hs
		843139 WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843273 WDR5B_HUMAN (180-476): 5.68e-43: 161: 13.40		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		196979 PRP4_HUMAN (2-175): 7.43e-33: 136: 12.85		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79