HitPredict

Interactor 1: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 974 Hs			1 2514
+	Hs
		1083443 RBBP7_HUMAN (43-334): 3.53e-61: 216: 20.46		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		1164188 BRWD3_HUMAN (3-209): 2.06e-31: 135: 10.79		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		1262850 PHIP_HUMAN (222-463): 1.44e-20: 100: 10.57		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		261584 TBL1R_HUMAN (138-486): 7.41e-43: 166: 12.16		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Mm
		1206586 TBL1R_MOUSE (135-486): 3.44e-43: 167: 12.33		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Mm
		1206786 TBL1X_MOUSE (142-486): 3.87e-42: 164: 13.13		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Hs
		1083357 RBBP7_HUMAN (43-334): 3.53e-61: 216: 20.46		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		1083355 RBBP7_HUMAN (43-334): 3.53e-61: 216: 20.46		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1281467 FBXW7_HUMAN (219-506): 1.23e-21: 102: 12.93		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		1262836 PHIP_HUMAN (222-463): 1.44e-20: 100: 10.57		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		1262828 PHIP_HUMAN (222-463): 1.44e-20: 100: 10.57		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		903450 WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		903374 WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		1262846 PHIP_HUMAN (222-463): 1.44e-20: 100: 10.57		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1346970 NLE1_HUMAN (3-88): 1.27e-17: 89.1: 7.78		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Dm
		1370295 POC1_DROME (135-343): 5.42e-37: 146: 16.27		Q9VLS7_DROME (674-1534): 4.08e-09: 64.5: 13.10
+	Hs
		297832 BRWD3_HUMAN (3-209): 2.06e-31: 135: 10.79		K0754_HUMAN (1962-2483): 2.12e-10: 69.1: 14.34
+	Hs
		1302927 NLE1_HUMAN (3-88): 1.27e-17: 89.1: 7.78		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		1281391 FBXW7_HUMAN (219-506): 1.23e-21: 102: 12.93		PRR36_HUMAN (2-1025): 1.03e-10: 69.6: 8.95
+	Dm
		1370257 MIO_DROME (21-223): 2.65e-20: 99.1: 9.57		Q9VLS7_DROME (674-1534): 4.08e-09: 64.5: 13.10