HitPredict

Interactor 1: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Interactor 2: H2B2F (Q5QNW6)
Histone H2B type 2-F (H2B-clustered histone 18)
Gene: H2BC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31839598, 35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 129 Hs			1 126
+	Hs
		1208878 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B2F_HUMAN (1-126): 7.69e-56: 171: 100.00
+	Hs
		659934 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B1O_HUMAN (1-126): 1.57e-55: 170: 98.41
+	Hs
		1163154 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B2E_HUMAN (1-126): 3.81e-55: 169: 97.62
+	Hs
		256960 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B1K_HUMAN (1-126): 7.94e-55: 169: 97.62
+	Hs
		449775 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B1J_HUMAN (1-126): 4.16e-55: 169: 96.83
+	Hs
		943408 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2BFS_HUMAN (1-126): 7.44e-55: 169: 96.03
+	Hs
		1401090 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B1N_HUMAN (1-126): 1.58e-54: 168: 97.62
+	Hs
		659896 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B1O_HUMAN (1-126): 1.57e-55: 170: 98.41
+	Hs
		754948 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B1B_HUMAN (1-126): 9.06e-55: 168: 96.03
+	Hs
		946861 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B1D_HUMAN (1-126): 1.77e-54: 168: 97.62
+	Hs
		1162786 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B2E_HUMAN (1-126): 3.81e-55: 169: 97.62
+	Hs
		1162858 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B1H_HUMAN (1-126): 3.2e-55: 169: 99.21
+	Hs
		256873 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B1K_HUMAN (1-126): 7.94e-55: 169: 97.62
+	Hs
		449723 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B1J_HUMAN (1-126): 4.16e-55: 169: 96.83
+	Hs
		943359 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2BFS_HUMAN (1-126): 7.44e-55: 169: 96.03
+	Hs
		754861 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B1B_HUMAN (1-126): 9.06e-55: 168: 96.03
+	Hs
		946788 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B1D_HUMAN (1-126): 1.77e-54: 168: 97.62
+	Hs
		1323960 H2A1A_HUMAN (1-129): 1.77e-67: 201: 92.25		H2B3B_HUMAN (1-126): 8.18e-53: 164: 95.24
+	Hs
		1162831 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B3B_HUMAN (1-126): 8.18e-53: 164: 95.24
+	Hs
		1162859 H2A2C_HUMAN (1-129): 7.14e-67: 199: 100.00		H2B1A_HUMAN (1-126): 3.11e-48: 152: 84.25