HitPredict

Interactor 1: CORO6 (Q6QEF8)
Coronin-6 (Coronin-like protein E) (Clipin-E)
Gene: CORO6

Interactor 2: POC1A (Q8NBT0)
POC1 centriolar protein homolog A (Pix2) (Proteome of centriole protein 1A) (WD repeat-containing protein 51A)
Gene: POC1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DUF1899~WD40, WD40~WD40, WD40~WD40_4
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 472 Hs			1 407
+	Hs
		678289 COR1A_HUMAN (1-463): 1.82e-110: 336: 67.24		POC1A_HUMAN (1-407): 1.25e-118: 352: 100.00
+	Hs
		678293 COR1A_HUMAN (1-463): 1.82e-110: 336: 67.24		POC1B_HUMAN (258-403): 3.81e-30: 122: 12.25
+	Hs
		792949 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		LIS1_HUMAN (141-406): 2.29e-77: 246: 20.21
+	Hs
		903418 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		FBXW7_HUMAN (131-406): 1.07e-65: 223: 20.79
+	Mm
		925836 LIS1_MOUSE (171-414): 4.42e-42: 156: 11.89		LIS1_MOUSE (141-406): 1.72e-77: 247: 20.21
+	Hs
		792935 LIS1_HUMAN (171-414): 5.36e-42: 155: 11.89		LIS1_HUMAN (141-406): 2.29e-77: 246: 20.21
+	Hs
		903428 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		SNR40_HUMAN (221-406): 1.38e-39: 146: 16.49
+	Hs
		903077 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		WDR5_HUMAN (259-406): 6.14e-34: 130: 15.44
+	Hs
		903551 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		NLE1_HUMAN (262-406): 1.23e-31: 127: 15.79
+	Hs
		903349 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		WDR5B_HUMAN (259-406): 1.83e-31: 123: 15.44
+	Hs
		196984 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		PRP4_HUMAN (316-406): 5.29e-10: 63.1: 5.00
+	Hs
		793026 LIS1_HUMAN (171-414): 5.36e-42: 155: 11.89		KTNB1_HUMAN (7-166): 6.66e-18: 87.8: 29.38
+	Hs
		1346954 NLE1_HUMAN (2-109): 2.01e-22: 101: 15.74		NLE1_HUMAN (262-406): 1.23e-31: 127: 15.79
+	Dm
		1358845 WDS_DROME (261-388): 1.53e-20: 94.6: 9.38		WDS_DROME (259-406): 1.13e-32: 127: 14.77
+	Hs
		921751 NLE1_HUMAN (2-109): 2.01e-22: 101: 15.74		GBB2_HUMAN (8-131): 4.26e-21: 95.3: 25.98
+	Hs
		245633 TBL1R_HUMAN (19-206): 8.36e-26: 112: 21.68		TBL1X_HUMAN (299-401): 6.04e-13: 72.4: 6.78
+	Dm
		1358859 WDS_DROME (261-388): 1.53e-20: 94.6: 9.38		FBXW7_DROME (15-218): 5.9e-18: 88.2: 29.95