HitPredict

Interactor 1: SMCL1 (Q18616)
Structural maintenance of chromosomes-like protein 1
Gene: smcl-1

Interactor 2: SMC4 (Q20060)
Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4)
Gene: smc-4

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28301465
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SMC_N~SMC_N
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 537 Ce			1 1549
+	Ce
		878244 SMCL1_CAEEL (1-537): 1.77e-90: 289: 100.00		DPY27_CAEEL (55-1366): 1.86e-100: 356: 27.91
+	Ce
		1068123 SMCL1_CAEEL (1-537): 1.77e-90: 289: 100.00		MIX1_CAEEL (90-1365): 2.29e-89: 320: 14.98
+	Hs
		334110 SMC2_HUMAN (6-463): 1.81e-45: 173: 11.66		SMC4_HUMAN (9-1370): 2.46e-104: 365: 28.67
+	Mm
		1362488 SMC1B_MOUSE (6-461): 7.87e-47: 177: 16.92		SMC1A_MOUSE (90-1371): 1.63e-80: 293: 18.09
+	Hs
		1130036 SMC1A_HUMAN (105-535): 5.47e-45: 172: 18.28		SMC1A_HUMAN (90-1371): 2.1e-80: 293: 18.01
+	Sc
		747769 SMC4_YEAST (150-535): 1.12e-44: 171: 14.95		SMC1_YEAST (90-1371): 3.05e-61: 233: 18.44
+	Sc
		864388 SMC4_YEAST (150-535): 1.12e-44: 171: 14.95		SMC3_YEAST (90-1374): 5.48e-61: 232: 15.06
+	Sc
		747711 SMC1_YEAST (6-426): 4.64e-44: 169: 17.92		SMC1_YEAST (90-1371): 3.05e-61: 233: 18.44
+	Xl
		896119 SMC4_XENLA (4-455): 2.27e-48: 182: 13.29		SMC2_XENLA (339-1368): 1.36e-51: 202: 14.77
+	Sp
		831744 SMC4_SCHPO (92-535): 1.54e-49: 185: 14.83		SMC2_SCHPO (355-1361): 1.5e-49: 195: 14.37
+	Bs
		908314 SMC_BACSU (6-396): 5.89e-45: 172: 14.22		SMC_BACSU (344-1374): 6.4e-47: 187: 14.22
+	Xl
		313473 SMC1A_XENLA (77-535): 5.48e-47: 178: 17.34		SMC3_XENLA (366-1378): 4.83e-44: 177: 12.99
+	Xl
		313481 SMC1A_XENLA (77-535): 5.48e-47: 178: 17.34		Q8AW91_XENLA (366-1378): 4.68e-43: 174: 12.89
+	Sc
		808614 SMC4_YEAST (150-535): 1.12e-44: 171: 14.95		SMC2_YEAST (338-1361): 4.53e-45: 180: 14.23
+	Mm
		1362489 SMC1B_MOUSE (6-461): 7.87e-47: 177: 16.92		SMC3_MOUSE (366-1378): 7.56e-41: 167: 12.70
+	Hs
		334127 SMC2_HUMAN (6-463): 1.81e-45: 173: 11.66		SMC3_HUMAN (366-1378): 8.67e-41: 167: 12.70
+	Hs
		1130223 SMC1A_HUMAN (105-535): 5.47e-45: 172: 18.28		SMC3_HUMAN (366-1378): 8.67e-41: 167: 12.70
+	Mm
		1423807 SMC1A_MOUSE (105-535): 5.32e-45: 172: 18.50		SMC3_MOUSE (366-1378): 7.56e-41: 167: 12.70
+	Bt
		357658 SMC1A_BOVIN (105-535): 5.17e-45: 172: 18.28		SMC3_BOVIN (366-1378): 2.92e-40: 165: 12.50