HitPredict

Interactor 1: I7GPR1 (I7GPR1)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (TRAF3-interacting protein 2)
Gene: Traf3ip2

Interactor 2: TRAF5 (P70191)
TNF receptor-associated factor 5
Gene: TRAF5

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	23042150
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 555 Mm			1 558
+	Mm
		999817 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF5_MOUSE (1-558): 1.17e-150: 445: 100.00
+	Mm
		1221531 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF3_MOUSE (2-557): 1.04e-125: 382: 41.71
+	Hs
		136647 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF5_HUMAN (1-558): 7.85e-147: 436: 79.57
+	Mm
		811922 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF2_MOUSE (18-555): 8.36e-102: 318: 30.11
+	Hs
		225411 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF3_HUMAN (4-557): 2.78e-123: 375: 41.43
+	Mm
		116909 I7GPR1_MOUSE (1-555): 0: 1019: 100.00		TRAF6_MOUSE (21-552): 1.52e-78: 258: 23.79
+	Mm
		999873 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF6_MOUSE (21-552): 1.52e-78: 258: 23.79
+	Mm
		999862 Q8C0E5_MOUSE (1-555): 0: 1014: 98.92		TRAF6_MOUSE (21-552): 1.52e-78: 258: 23.79
+	Hs
		225408 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF2_HUMAN (18-555): 8.36e-102: 318: 28.83
+	Mm
		1222722 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF4_MOUSE (29-552): 3.12e-61: 211: 22.62
+	Hs
		225409 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF1_HUMAN (161-553): 6.03e-79: 256: 31.49
+	Hs
		225437 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF6_HUMAN (2-552): 9.57e-77: 253: 22.44