HitPredict

Interactor 1: I7GPR1 (I7GPR1)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (TRAF3-interacting protein 2)
Gene: Traf3ip2

Interactor 2: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23042150
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 555 Mm			1 530
+	Mm
		999873 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF6_MOUSE (1-530): 5.81e-137: 408: 100.00
+	Mm
		999862 Q8C0E5_MOUSE (1-555): 0: 1014: 98.92		TRAF6_MOUSE (1-530): 5.81e-137: 408: 100.00
+	Hs
		225437 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF6_HUMAN (1-530): 2.33e-139: 414: 87.93
+	Mm
		811922 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF2_MOUSE (38-508): 1.78e-101: 316: 25.75
+	Mm
		1222722 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF4_MOUSE (54-515): 1.24e-88: 282: 25.47
+	Mm
		1221531 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF3_MOUSE (14-510): 1.65e-86: 279: 21.64
+	Mm
		116908 I7GPR1_MOUSE (1-555): 0: 1019: 100.00		TRAF5_MOUSE (43-508): 1.42e-81: 266: 24.54
+	Mm
		999817 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF5_MOUSE (43-508): 1.42e-81: 266: 24.54
+	Hs
		225408 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF2_HUMAN (38-508): 3.93e-101: 315: 25.55
+	Hs
		225411 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF3_HUMAN (14-510): 3.16e-85: 276: 20.94
+	Hs
		136647 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF5_HUMAN (43-508): 9.42e-81: 264: 24.35
+	Hs
		225409 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF1_HUMAN (50-511): 1.91e-64: 217: 18.63