Interactor 1: SYNE2 (Q6ZWQ0)
Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)
Gene: SYNE2

Interactor 2: SUN2 (Q8BJS4)
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Sad1/unc-84 protein-like 2)
Gene: SUN2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.854

The method score is based on:

Property Details
Experiments 16380439, 26688217, 22349700
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains KASH~Sad1_UNC
Common GO terms GO:0005635 - nuclear envelope
GO:0021817 - nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration
GO:0030335 - positive regulation of cell migration
GO:0031022 - nuclear migration along microfilament
GO:0034993 - meiotic nuclear membrane microtubule tethering complex
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 6874
Mm

1 731
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024