HitPredict

Interactor 1: RGL3 (Q3MIN7)
Ral guanine nucleotide dissociation stimulator-like 3 (RalGDS-like 3)
Gene: RGL3

Interactor 2: RIT2 (Q99578)
GTP-binding protein Rit2 (EC 3.6.5.2) (Ras-like protein expressed in neurons) (Ras-like without CAAX protein 2)
Gene: RIT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RA~Ras, Ras~RasGEF, Ras~RasGEF_N
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 710
Hs

1 217
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Service provided by Combinatics, Japan

Last updated: 11Aug2025