Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS
Interactor 2: RGL1 (Q9NZL6)
Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1)
Gene: RGL1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.76 | 1.00 | 0.875 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 20936779, 24441586 |
| Identification Methods | affinity chromatography technology, two hybrid, isothermal titration calorimetry, nuclear magnetic resonance, two hybrid pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RA~Ras, Ras~RasGEF, Ras~RasGEF_N |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007265 - Ras protein signal transduction |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
