HitPredict

Interactor 1: RASN (P08556)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: Nras

Interactor 2: RGL2 (Q61193)
Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like 2) (RalGDS-like factor) (Ras-associated protein RAB2L)
Gene: RGL2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RA~Ras, Ras~RasGEF, Ras~RasGEF_N
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Mm			1 778
+	Mm
		746560 RASK_MOUSE (1-189): 1.33e-85: 251: 86.77		RGL2_MOUSE (11-778): 0: 870: 100.00
+	Hs
		182033 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		RGL2_HUMAN (11-778): 0: 831: 89.45
+	Hs
		374976 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		RGL1_HUMAN (49-761): 0: 610: 30.54
+	Mm
		1190994 RASH_MOUSE (1-188): 8.11e-90: 262: 86.70		RGL3_MOUSE (42-738): 0: 561: 34.36
+	Hs
		374640 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		RGL3_HUMAN (42-737): 0: 542: 34.05
+	Ce
		109117 LET60_CAEEL (1-181): 1.74e-88: 259: 76.80		G4SFM6_CAEEL (59-771): 1.73e-172: 520: 23.97
+	Ce
		653997 LET60_CAEEL (1-181): 1.74e-88: 259: 76.80		Q19852_CAEEL (59-771): 3.76e-169: 512: 23.32
+	Dm
		473609 RAS1_DROME (1-165): 2.19e-90: 264: 85.46		Q86BI2_DROME (45-740): 3.78e-166: 501: 26.69
+	Dm
		473617 RAS1_DROME (1-165): 2.19e-90: 264: 85.46		Q9GR11_DROME (45-740): 4.3e-166: 500: 26.69
+	Dm
		473618 RAS1_DROME (1-165): 2.19e-90: 264: 85.46		Q9U4U5_DROME (45-740): 2.54e-161: 494: 26.69
+	Hs
		374546 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		SOS1_HUMAN (39-695): 8.53e-148: 468: 20.37
+	Hs
		374591 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		RGRF1_HUMAN (19-516): 3.1e-108: 360: 20.66
+	Hs
		374736 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		GRP3_HUMAN (93-769): 7.04e-107: 344: 18.20
+	Hs
		374590 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		RPGF1_HUMAN (13-526): 1.52e-99: 333: 22.33
+	Hs
		374724 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		RGPS2_HUMAN (200-620): 1.45e-92: 303: 21.61
+	Hs
		374747 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		RGDSR_HUMAN (227-514): 1.6e-90: 294: 33.79
+	Mm
		1042543 RASH_MOUSE (1-188): 8.11e-90: 262: 86.70		GNDS_MOUSE (52-241): 9.35e-27: 118: 20.89
+	Hs
		374558 RASH_HUMAN (1-188): 8.11e-90: 262: 86.70		GNDS_HUMAN (10-220): 7.19e-26: 116: 20.33
+	Ce
		111626 LET60_CAEEL (1-181): 1.74e-88: 259: 76.80		RPGF_CAEEL (213-413): 1.58e-11: 70.5: 27.86
+	Ce
		653996 LET60_CAEEL (1-181): 1.74e-88: 259: 76.80		Q19770_CAEEL (163-482): 1.35e-10: 67: 21.30